Prevalence of Nosocomial Diarrhea Due to Adenoviruses 40 and 41 in a Paediatric Ward in Iran
Published: December 1, 2015 | DOI: https://doi.org/10.7860/JCDR/2015/.6976
Abolfazl Khoshdel, Neda Parvin, Abbas Doosti, Fatemeh Famouri
1. Associate Professor, Department of Pediatrics, Shahrekord University of Medical Sciences, Shahrekord, Iran.
2. Lecturer, Department of Nursing, Shahrekord University of Medical Sciences, Shahrekord, Iran.
3. Assistant Professor, Department of Genetics, Islamic Azad University Shahrekord Branch, Shahrekord, Iran.
4. Assistant Professor, Department of Pediatrics, Isfahan University of Medical Sciences, Isfahan, Iran.
Correspondence
Dr. Neda Parvin,
Lecturer, Nursing Department, Shahrekord University of Medical Sciences, Rahmatiyeh, Shahrekord, Iran.
E-mail : np285@yahoo.com
Background: Enteric adenoviruses 40 (Ad40) and adenovirus 41 (Ad41) have been shown to be a significant cause of paediatric gastroenteritis worldwide, but no data are available for nosocomial diarrhea due to adenovirus in Iran.
Aim: The present study was performed to determine the incidence of Ad40 and Ad41 in children less than five years with nosocomial diarrhea in Shahrekord, southwest Iran.
Materials and Methods: Adenovirus was detected by polymerase chain reaction (PCR) in stool samples collected during one year (2010-2011) from children less than five years with nosocomial diarrhea admitted to a paediatric center in Shahrekord, Iran. Nosocomial diarrhea was defined as those occurring more than 72 hours after admission to hospital for non-diarrheal causes. PCR technique was used for investigation of Ad40 and Ad41.
Results: In total of 100 samples, Ad40 and Ad41 DNA was found to be positive in 14/100 (14%), and 8/100 (8%) of diarrheic patients less than five years, respectively.
Conclusion: Ad40 and Ad41 are important causes of nosocomial diarrhea in less than five-year, hospitalized Iranian children.
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